The structure of nucleic acids, DNA and RNA, differ in that aDNA contains a nucleotide with thymine, while RNA contains a nucleotide with uracil. bDNA's nucleotide sequence is single stranded, while RNA's nucleotide sequence is double stranded. cRNA's backbone is made up of phosphates, while DNA's backbone is made up of nitrates. dRNA contains only three different nucleotides, while DNA contains four different nucleotides.