1 Coulomb of charge = 6.25*1018 . How?

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I don't understand the question.  It seems the same as asking "How is 1 mile 5,280 feet ?"The amount of charge on every electron and every proton is the same.  For human people, it's a very small amount of charge, so we work with a larger unit, called the Coulomb.  That's the amount of charge on 6.25 x 10¹⁸ electrons.In a wire, when that many electrons, carrying that amount of charge, pass by some point every second, we call the current in the wire 1 Ampere.

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